Six games on the Wednesday college basketball schedule feature a ranked team, including the matchup between the Kansas Jayhawks and the Iowa State Cyclones. Below, we provide against-the-spread picks for each contest.

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AP Top 25 Picks ATS Today

No. 2 Iowa State Cyclones vs. No. 9 Kansas Jayhawks

Spread Prediction

• Computer Prediction: Iowa State 75, Kansas 71
• Projected Favorite: Iowa State by 3.6 points
• Pick ATS: Kansas (+5.5)

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Key Facts

• Time: 7:00 PM ET
• Location: Ames, Iowa
• Venue: James H. Hilton Coliseum
• TV Channel: ESPN2
• Live Stream: Watch this game on Fubo (Regional restrictions may apply)

No. 12 Michigan State Spartans vs. Penn State Nittany Lions

Spread Prediction

• Computer Prediction: Michigan State 81, Penn State 71
• Projected Favorite: Michigan State by 10 points
• Pick ATS: Penn State (+12.5)

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Key Facts

• Time: 7:30 PM ET
• Location: East Lansing, Michigan
• Venue: Jack Breslin Students Events Center
• TV Channel: BTN
• Live Stream: Watch this game on Fubo (Regional restrictions may apply)

No. 6 Tennessee Volunteers vs. No. 23 Georgia Bulldogs

Spread Prediction

• Computer Prediction: Tennessee 74, Georgia 65
• Projected Favorite: Tennessee by 9.1 points
• Pick ATS: Georgia (+11.5)

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Key Facts

• Time: 8:00 PM ET
• Location: Knoxville, Tennessee
• Venue: Thompson-Boling Arena
• TV Channel: SEC Network
• Live Stream: Watch this game on Fubo (Regional restrictions may apply)

No. 10 Houston Cougars vs. West Virginia Mountaineers

Spread Prediction

• Computer Prediction: Houston 74, West Virginia 61
• Projected Favorite: Houston by 13 points
• Pick ATS: West Virginia (+17.5)

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Key Facts

• Time: 8:00 PM ET
• Location: Houston, Texas
• Venue: Fertitta Center
• TV Channel: ESPN+
• Live Stream: Watch this game on ESPN+

Washington Huskies vs. No. 17 Purdue Boilermakers

Spread Prediction

• Computer Prediction: Purdue 77, Washington 69
• Projected Favorite: Purdue by 8.1 points
• Pick ATS: Purdue (-7.5)

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Key Facts

• Time: 9:30 PM ET
• Location: Seattle, Washington
• Venue: Alaska Airlines Arena at Hec Edmundson Pavilion
• TV Channel: BTN
• Live Stream: Watch this game on Fubo (Regional restrictions may apply)

UNLV Rebels vs. No. 22 Utah State Aggies

Spread Prediction

• Computer Prediction: Utah State 77, UNLV 70
• Projected Favorite: Utah State by 7.2 points
• Pick ATS: Utah State (-4.5)

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Key Facts

• Time: 11:00 PM ET
• Location: Las Vegas, Nevada
• Venue: Thomas & Mack Center
• TV Channel: CBS Sports Network
• Live Stream: Watch this game on Fubo (Regional restrictions may apply)

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